EVALUATION OF THE EFFECT OF ANTIRESORPTIVE THERAPY ON THE DYNAMICS OF BONE METABOLISM MARKERS IN PATIENTS WITH DIABETIC CHARCOT OSTEOARTHROPATHY

Tojiboyev Salimjon Sodiq  ugli; Kamalov Telman  Toʻlaganovich

Authors

Tojiboyev Salimjon Sodiq ugli Doctor - resident at the department of reconstructive plastic surgery for complications of diabetes mellitus RSNPMCE named after. Y.H. Turakulova
Kamalov Telman Toʻlaganovich Doctor of Medical Sciences, Head of the Department of Reconstructive Plastic Surgery for Complications of Diabetes Mellitus, RSNPMCE named after. Y.H. Turakulova

Keywords:

type 2 diabetes mellitus, Sharko foot, bone metabolism, markers

Abstract

Before treatment, there was a significant decrease in the values of total calcium, ionized calcium, creatinine, GFR, osteocalcin, Vit D, beta-cross laps, calcitonin, procalcitonin, which were significantly lower than in the control group against the background of high PTH values and the development of secondary hyperparathyroidism. Further, after 6 months of treatment, there is a significant improvement in such indicators of bone metabolism as the average levels of total calcium (p<0.001), ionized calcium (p<0.001), Vitamin D (p<0.001), PTH (p<0.001), ostase (p <0.001), B-cross laps (p<0.001) and calcitonin (p<0.001) in groups 1 and 2 of patients.