EVALUATION OF THE EFFECT OF ANTIRESORPTIVE THERAPY ON THE DYNAMICS OF BONE METABOLISM MARKERS IN PATIENTS WITH DIABETIC CHARCOT OSTEOARTHROPATHY

Abstract

Before treatment, there was a significant decrease in the values of total calcium, ionized calcium, creatinine, GFR, osteocalcin, Vit D, beta-cross laps, calcitonin, procalcitonin, which were significantly lower than in the control group against the background of high PTH values and the development of secondary hyperparathyroidism. Further, after 6 months of treatment, there is a significant improvement in such indicators of bone metabolism as the average levels of total calcium (p<0.001), ionized calcium (p<0.001), Vitamin D (p<0.001), PTH (p<0.001), ostase (p <0.001), B-cross laps (p<0.001) and calcitonin (p<0.001) in groups 1 and 2 of patients.